Related topics: cells · protein · dna · genetic material · dna sequences

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Scientists have learned how plants keep viruses from being passed to their offspring, a finding that could ensure healthier crops. The discovery could also help reduce the transmission of diseases from mothers to human children.

Glitch in protein synthesis could affect tumor growth

During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together of amino acids—the building blocks of proteins. As the translation machinery carouses along the ...

New tools for fungicide resistance detection

Researchers at the Center for Crop and Disease Management (CCDM) have developed a new method for detecting fungicide resistance, enabling them to detect multiple mutations, both known and novel, in just one test.

How duplicated genomes helped grasses diversify and thrive

Grasses cover about 40% of the Earth's land surface, thriving in a multitude of environments. The evolutionary success of this plant family, which includes rice, maize, wheat and bamboo, likely results from a history of whole-genome ...

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DNA sequence

A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.

The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."

Sequences can be derived from the biological raw material through a process called DNA sequencing.

In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:

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