Related topics: mass spectrometry · protein

Scientists use carbon isotopes to track 'forever chemicals'

Organofluorine compounds—sometimes called "forever chemicals"—are increasingly turning up in our drinking water, oceans and even human blood, posing a potential threat to the environment and human health.

NASA trains machine learning algorithm for Mars sample analysis

When a robotic rover lands on another world, scientists have a limited amount of time to collect data from the troves of explorable material, because of short mission durations and the length of time to complete complex experiments.

Strawberries under the high-tech magnifying glass

Sweet flavors and healthy ingredients make strawberries one of the world's most popular berries. The complex biochemical compounds that determine the flavor and nutritional value of a strawberry—known as biomarkers—can ...

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Mass spectrometry

Mass spectrometry (MS) is an analytical technique for the determination of the elemental composition of a sample or molecule. It is also used for elucidating the chemical structures of molecules, such as peptides and other chemical compounds. The MS principle consists of ionizing chemical compounds to generate charged molecules or molecule fragments and measurement of their mass-to-charge ratios. In a typical MS procedure:

MS instruments consist of three modules: an ion source, which can convert gas phase sample molecules into ions (or, in the case of electrospray ionization, move ions that exist in solution into the gas phase); a mass analyzer, which sorts the ions by their masses by applying electromagnetic fields; and a detector, which measures the value of an indicator quantity and thus provides data for calculating the abundances of each ion present. The technique has both qualitative and quantitative uses. These include identifying unknown compounds, determining the isotopic composition of elements in a molecule, and determining the structure of a compound by observing its fragmentation. Other uses include quantifying the amount of a compound in a sample or studying the fundamentals of gas phase ion chemistry (the chemistry of ions and neutrals in a vacuum). MS is now in very common use in analytical laboratories that study physical, chemical, or biological properties of a great variety of compounds.

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