https://phys.org/nanotech-news/bio-medicine en-us The latest science news on nanobiology, nano medicine, nanotechnology, nanoscience, and nanotech. Each year, about 2.2 million bone-grafting procedures are performed worldwide, the gold standard of care being autografting, which uses the patient's own bone for tooth implantation and to repair and reconstruct parts of the mouth, face and skull. https://phys.org/news/2024-09-bone-grafts-nanofibrous-scaffolds-main.html Bio & Medicine Thu, 26 Sep 2024 16:30:03 EDT news646587001 Many cellular functions in the human body are controlled by biological droplets called liquid-liquid phase separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside living cells but are not enclosed by membranes like most cell structures. https://phys.org/news/2024-09-scientists-method-synthetic-dna-droplet.html Bio & Medicine Thu, 26 Sep 2024 14:00:10 EDT news646578001 A toothpaste-based transistor is the latest innovation from the research team at the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) in Milan, which pushes the boundaries of edible electronics. This innovative nano-device is expected to become a key component of future smart pills, designed to monitor health conditions from within the body and then safely dissolve after completing their function. The research findings have been published in the journal Advanced Science. https://phys.org/news/2024-09-edible-toothpaste-based-transistor.html Bio & Medicine Nanomaterials Thu, 26 Sep 2024 10:36:46 EDT news646565801 A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is published in the journal Nature. https://phys.org/news/2024-09-biologists-sequence-proteins-nanopores.html Bio & Medicine Thu, 26 Sep 2024 10:32:26 EDT news646565540 With strong bactericidal properties, graphene has the potential to become a game changer in the fight against antibiotic-resistant bacteria. So far there have been no efficient ways to control these properties—and thus no way to make use of graphene's potential in health care. https://phys.org/news/2024-09-graphene-spike-mat-ordinary-fridge.html Bio & Medicine Nanomaterials Tue, 24 Sep 2024 12:50:12 EDT news646401006 It's almost time to dust off the Halloween decorations and adorn the house with all manner of spooky things, including the classic polyester spider webs. Scientists reporting in ACS Nano have made their own version of fake spider silk, but this one consists of proteins and heals wounds instead of haunting hallways. The artificial silk was strong enough to be woven into bandages that helped treat joint injuries and skin lesions in mice. https://phys.org/news/2024-09-artificial-spider-silk-generation-medical.html Bio & Medicine Tue, 24 Sep 2024 11:50:03 EDT news646397402 In a study published July 29 in Advanced Materials, University of Texas at Dallas researchers found that X-rays of the kidneys using gold nanoparticles as a contrast agent might be more accurate in detecting kidney disease than standard laboratory blood tests. Based on their study in mice, they also found that caution may be warranted in employing renal-clearable nanomedicines to patients with compromised kidneys. https://phys.org/news/2024-09-blood-nanoparticle-potential-kidneys.html Bio & Medicine Sat, 21 Sep 2024 11:16:35 EDT news646136152 In a study published in Advanced Functional Materials, a research team from the Shanghai Institute of Materia Medica (SIMM) of the Chinese Academy of Sciences developed an oral molecular targeted drug delivery system based on an inulin derivative, which combines gut microbiota modulation with precise drug delivery, enhancing colorectal cancer (CRC) therapy. https://phys.org/news/2024-09-scientists-prebiotic-carrier-regorafenib-colorectal.html Bio & Medicine Nanomaterials Fri, 20 Sep 2024 13:04:54 EDT news646056284 Diabetes, a widespread condition affecting approximately 13% of American adults, is often accompanied by complications such as impaired wound healing. If left unchecked, this can lead to severe outcomes, including the need for amputation. https://phys.org/news/2024-09-harnessing-exosomes-hydrogels-advanced-diabetic.html Bio & Medicine Fri, 20 Sep 2024 12:18:58 EDT news646053534 When we need to recharge, we might take a vacation or relax at the spa. But what if we could recharge at the cellular level, fighting against aging and disease with the microscopic building blocks that make up the human body? https://phys.org/news/2024-09-recharging-mitochondria-nanoflowers-simulate-energy.html Bio & Medicine Fri, 20 Sep 2024 12:17:04 EDT news646053421 RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short interfering RNA (siRNA) remain key challenges for its clinical application. https://phys.org/news/2024-09-cholesterol-exosome-rna-drug-delivery.html Bio & Medicine Fri, 20 Sep 2024 11:30:03 EDT news646050601 In a study published in Nature Nanotechnology, researchers discovered that cuproptosis may serve as a new target for radiosensitization in re-irradiation. https://phys.org/news/2024-09-copper-based-nanocapsules-shown-radiotherapy.html Bio & Medicine Nanomaterials Fri, 20 Sep 2024 11:17:22 EDT news646049838 Like moths to a flame, microbes can also be moved by light. Using this knowledge, researchers from Osaka Metropolitan University's Research Institute for Light-induced Acceleration System (RILACS) have demonstrated a method to detect the presence of viruses quickly and using only a small sample. https://phys.org/news/2024-09-immunoassay-coronavirus-spike-proteins-minutes.html Bio & Medicine Nanomaterials Thu, 19 Sep 2024 10:02:02 EDT news645958921 The importance of testing for diseases was thrust into the limelight during the COVID-19 pandemic. Many of us have undergone a PCR (Polymerase Chain Reaction) or ELISA (Enzyme-Linked Immunosorbent Assay) test within the past four years. https://phys.org/news/2024-09-janus-particles-rapidly-accurately-covid.html Bio & Medicine Thu, 19 Sep 2024 09:24:57 EDT news645956693 Depression is a significant challenge to diagnose and treat. Among the factors influencing depression onset and severity, there is growing evidence for chemical imbalances that generate oxidative stress throughout the body. To address this problem, researchers reporting in the journal Langmuir have developed antioxidant carbon dot nanozymes (synthetic enzyme-like substances) that reduced oxidative stress, rebalanced gut microbes and alleviated stress-induced depression in rats. https://phys.org/news/2024-09-antioxidant-carbon-dot-nanozymes-alleviate.html Bio & Medicine Wed, 18 Sep 2024 17:08:06 EDT news645898081 Atherosclerosis is the build-up of plaque in the arteries which causes their narrowing. It is a primary cause of ischemic heart disease (IHD) and ischemic stroke (IS), both of which are major contributors to the 17.9 million deaths caused by cardiovascular diseases each year globally. The incidence of atherosclerosis-related conditions has been rising steadily over the past three decades, and particularly in younger populations. The increase is driven by lifestyle factors such as unhealthy diets, lack of exercise, smoking, and alcohol consumption. https://phys.org/news/2024-09-nanoparticle-technology-diagnosis-treatment-atherosclerosis.html Bio & Medicine Wed, 18 Sep 2024 16:38:27 EDT news645896304 As the use of electronic devices continues to rise, the management of electronic waste (e-waste) has become a critical issue. Printed circuit board (PCB) recycling methods are generally classified into physical and chemical approaches. https://phys.org/news/2024-09-upcycling-heterogeneous-cuo-nano-skeletons.html Bio & Medicine Nanomaterials Wed, 18 Sep 2024 14:45:03 EDT news645889501 In the world of nanotechnology, the development of dynamic systems that respond to molecular signals is becoming increasingly important. The DNA origami technique, whereby DNA is programmed so as to produce functional nanostructures, plays a key role in these endeavors. https://phys.org/news/2024-09-dna-origami-fluorescent-probes-precisely.html Bio & Medicine Nanophysics Wed, 18 Sep 2024 12:17:03 EDT news645880621 Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA and potent drugs directly into cells, potentially leading to a more effective treatment of diseases. https://phys.org/news/2024-09-method-rna-drugs-cells.html Bio & Medicine Nanomaterials Mon, 16 Sep 2024 16:24:04 EDT news645722642 Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively. The treatment involves using substances that boost the immune system, teaching immune cells to target cancer, or using engineered cells to specifically target and kill cancer cells. https://phys.org/news/2024-09-nano-sized-cell-particles-boost.html Bio & Medicine Mon, 16 Sep 2024 10:14:02 EDT news645700436 A research group from Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS) developed a novel method for idiopathic pulmonary fibrosis (IPF) therapy by transplanting mesenchymal stem cells (MSCs), which improved the therapeutic efficacy and realized real-time treatment visualization. The study was published in Science Advances. https://phys.org/news/2024-09-trimetallic-based-nanocarriers-method-visualized.html Bio & Medicine Mon, 16 Sep 2024 09:47:03 EDT news645698821 A team of researchers at NYU Abu Dhabi (NYUAD), led by Program Head of Chemistry Ali Trabolsi, have developed nanoscale covalent organic frameworks (nCOFs), crystalline organic polymers that have been modified with peptides to treat the most aggressive form of breast cancer, known as triple-negative breast cancer (TNBC). https://phys.org/news/2024-09-covalent-frameworks-precise-cancer-treatment.html Bio & Medicine Fri, 13 Sep 2024 14:01:03 EDT news645454861 What do firefighting foam, non-stick cookware, water-repellent textiles and pesticides all have in common? They all contain per- and polyfluoroalkyl substances, or PFAS—human-made chemicals that don't break down naturally. It's no wonder, then, that PFAS are now contaminating soil and water and can also be detected in the bodies of humans and animals. The dangers are well known: these forever chemicals can damage the liver, trigger hormonal disorders and cause cancer, to mention just a few of their effects. https://phys.org/news/2024-09-method-chemicals-nanoparticles-ultrasound.html Bio & Medicine Nanomaterials Fri, 13 Sep 2024 09:29:23 EDT news645438559 Scientists have found a new way to see how butterflies develop their colors. https://phys.org/news/2024-09-hyperspectral-microscopy-reveals-nanostructures-butterflies.html Bio & Medicine Wed, 11 Sep 2024 13:03:59 EDT news645278630 A new diagnostic test system jointly developed at the University of Chicago Pritzker School of Molecular Engineering (PME) and UCLA Samueli School of Engineering fuses a powerful, sensitive transistor with a cheap, paper-based diagnostic test. When combined with machine learning, the system becomes a new kind of biosensor that could ultimately transform at-home testing and diagnostics. https://phys.org/news/2024-09-diagnostic-combines-technologies-machine-paradigm.html Bio & Medicine Tue, 10 Sep 2024 15:23:04 EDT news645200582 Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have developed a biosensor that improves sensitivity to 1-methylnicotinamide (1-MNA) in urine by orders of magnitude without the need for sample purification. The work is published in the journal Analytical Chemistry. https://phys.org/news/2024-09-high-throughput-biosensor-metabolite-disease.html Bio & Medicine Tue, 10 Sep 2024 15:11:50 EDT news645199908 Biomolecules-based materials hold great promise for malignant tumor phototherapy. However, current supramolecular biomaterials primarily suffer from poor tissue penetration, inadequate tumor accumulation, and particularly neglecting the unique benefits of chirality, thus significantly limiting their phototherapeutic efficacy. https://phys.org/news/2024-09-quantum-dot-hydrogel-photothermal-conversion.html Bio & Medicine Tue, 10 Sep 2024 14:48:41 EDT news645198510 Researchers at the University of Chicago Medicine Comprehensive Cancer Center have developed a nanomedicine that increases the penetration and accumulation of chemotherapy drugs in tumor tissues and effectively kills cancer cells in mice. https://phys.org/news/2024-09-experimental-nanomedicine-chemo-drugs-tumors.html Bio & Medicine Tue, 10 Sep 2024 10:44:04 EDT news645183841 Recently, a collaborative research team led by Prof. Wang Hui and Prof. Qian Junchao from Hefei Institutes of Physical Science of the Chinese Academy of Sciences designed a catalytically active, photoresponsive, Fe-doped carbon nanoparticle (FDCN) for second near-infrared (NIR-II) window, photothermal-enhanced chemodynamic therapy. https://phys.org/news/2024-09-iron-doped-carbon-based-nanoparticles.html Bio & Medicine Tue, 10 Sep 2024 10:35:03 EDT news645183301 Developing antiviral therapeutics and vaccines requires close study of the viruses that cause disease. But how can these small germs be isolated from complex biological samples like saliva? https://phys.org/news/2024-09-viruses-saliva-therapeutic.html Bio & Medicine Mon, 09 Sep 2024 14:55:03 EDT news645112501